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Professional instruction often identifies inefficient movement patterns contributing to injury

To put it into perspective, weight loss surgeries like gastric bypass typically lead to 25-30% total body weight loss, meaning tirzepatide approaches surgical-level results

The Benefit Appears Before Significant Weight Loss Even Occurs Another compelling piece of evidence is the timing of the cardiovascular benefit

The Image J software (version 1.53 K, National Institutes of Health, USA) was used to determine the average optical density of positive tissue in each field

Acknowledgments We would like to thank Biorender for providing the professionally designed figure elements to the manuscript

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