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The pressure gradient between the stomach and duodenum also influences the rate at which liquids empty

However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug

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Presented for research literature review only Szczepankiewicz BG et al

Although the precise mechanism by which these LXR agonists effect a reduction in the progression of atherosclerosis is not clear, it is known that the genes encoding ABCA1 and ABCG1 contain LXR-binding sites