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CircZBTB46 counteracts the inhibitory effect of miR326 on FGF1/AMPK by acting as a miR-326 sponge, promoting the expression of FGF1, and thus reducing hepatic lipid deposition
However, the large number of significant correlations noted in this study between Parasutterella relative abundance and EWAT metabolites strongly supports the relevance of this genus to the EWAT metabolome
It also may inhibit follicular miniaturization signals (such as certain transforming growth factor pathways)
Together, they maximize both the local signal and the system-wide cell mobilization needed for complex connective tissue repair
Cl: Clearance
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