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Glutathione Conjugation (GST Enzymes) Glutathione S-transferases (GSTs) catalyze the conjugation of reduced glutathione (GSH) to electrophilic substrates
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It's not dangerous, but it can: Add 13kg of scale weight (masking actual fat loss) Cause visible puffiness in legs or hands Be uncomfortable if severe What to do if you notice edema: Reduce KLOW dose by 50% and reassess after 2 weeks If on a daily frequency, drop to 3x/week If it persists, switch to pinning BPC-157 and GHK-Cu separately, leaving TB-500 out until the edema resolves Stay well-hydrated (counterintuitively, more water can help flush the retained fluid) Most people find edema resolves once the body adapts in weeks 24, or by reducing frequency
2023 Nov 30;21(4):758-768
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