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Challenges and Considerations Despite its promise, retatrutide faces challenges

The studies on potential DDI with GLP1RAs showed absence of clinically significant effects on the PK and PD of drugs from the four BCS classes

Future research The clinical development of retatrutide is ongoing, with several phase 3 trials, collectively known as the TRIUMPH program, currently underway

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Proc Natl Acad Sci U S A 1989;86:39537.ArticlePubMedPMC 29