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Sep 9 2020;370:m3222
We dont have the equivalent knowledge of whats causing the obesity epidemic so we cant say its the drug or this dietary approach
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The NICE criteria are as follows: NICE recommends GLP-1 analogues or Tirzepatide (Mounjaro) for the treatment of adults with type 2 diabetes alongside diet and exercise when diabetes is insufficiently controlled, only if: triple therapy with metformin and 2 other oral antidiabetic drugs is ineffective, not tolerated or contraindicated, and a person has a body mass index (BMI) of 35 kg/m2 or more, and specific psychological or other medical problems associated with obesity, or a person has a BMI of less than 35 kg/m2, and: Insulin therapy would have significant occupational implications, or Weight loss would benefit other significant obesity-related complications
These substances mix easily with water for the same reason that ethanol mixes easily with water
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