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Isolated reports suggest creatine may be associated with various side effects affecting several organ systems including skeletal muscle, the kidney and the gastrointestinal tract, stated a review in Sub-Cellular Biochemistry
Intestinal mucosal iron transport is defective in two mutant strains
Cosmeceuticals and Active Cosmetics, 2nd Ed., CRC Press, 549-563
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It also helps reduce markers of metabolic stress
Rett syndrome (RS) is caused by mutations in the gene methyl-CpG-binding protein 2 (MECP2) Rett syndrome RS is characterized by language and communication problems, learning and coordination difficulties, and they display autistic-like behaviors [362, 363]
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