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Efficacy threshold
It is an investigational research compound that has not been approved for human use by the TGA
In excess, this causes water retention, mood changes, and tissue sensitivity
Hydrolysis: Once a peptide is dissolved in aqueous solution, water molecules attack the peptide backbone, cleaving amide bonds
Its high reactivity limits its diffusion, causing damage to macromolecules like cell membranes, proteins, and DNA [55, 56]
Interestingly, these pharmacological concentrations align closely with peak levels of endogenous GLP-1 observed during intense physiological stimulation [120, 121]
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