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Although ponatinib is an FDA-approved TKI that directly targets T315I-Bcr-Abl leukemia, its association with cardiovascular toxicity is a significant concern in clinical therapy
They are also contraindicated in those with personal or family history of medullary thyroid carcinoma and those with multiple endocrine neoplasia type 2
If the California Board decides your documentation is thin, they can shut you down even if the FDA hasnt said a word
For some patients, medication may be long-term
If your pen window shows anything besides crystal clear liquid, stop and call your doctor for assistance
Patients should attend scheduled diabetes reviews and report any difficulties with the medication to their GP or diabetes specialist nurse
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