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Youve gotta stick to both if you want to lose weight and keep it off
Long-term adherence matters most: patients who continue tirzepatide for 12+ months maintain 8590% of achieved weight loss, while those who stop often regain 3050% within 6 months
However, the elevated heart rate means monitoring becomes important during intense exercise
This would be consistent with other research on the impact of GLP-1 drugs for obesity on medical budgets: Institute for Clinical and Economic Review (ICER) 2022: Lifetime cost of drugs $274K
SGLT2i should be continued until end-stage kidney disease (dialysis or kidney transplant)
It was also reported by 5% of patients taking Wegovy tablet
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