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The connection between caloric restriction, increased fat mobilization demand, and the need for efficient mitochondrial fatty acid transport is well-established in biochemistry

The complex pathophysiology and the metabolic risk factors shared between type 2 diabetes, obesity, CKD and cardiovascular disease have led to the concept of a cardiovascularkidneymetabolic (CKM) syndrome

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doi: 10.1038/nature05414 106 RidauraVKFaithJJReyFEChengJDuncanAEKauALet al

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