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Long-chain fatty acids and phospholipids like lysophosphatidylcholine (LPC), other compounds such as retinoic acid (RA) and multiple N-acylethanolamines (NAE) such as N-oleyldopamine (OLDA), palmitoylethanolamide (PEA), or oleylethanolamide (OEA), all act as endogenous ligands of GPR119

These factors suggest that hair loss may not directly result from GLP-1 medications but rather from the changes they induce in your body, but more research is needed to fully understand the connection

MG Traber, JF Vitamins C and E: beneficial effects from a mechanistic perspective

Lancet Gastroenterol Hepatol 2023;8:17991.ArticlePubMed 82

This is not well understood mechanistically but may relate to individual sensitivity, dehydration, or unrelated factors coinciding with supplement use

Circulation (2004) 109:9625