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The SELECT trial in non-diabetic patients with cardiovascular disease demonstrated a 20% reduction in heart attacks and strokes
10.1016/S1474-4422(09)70014-6 106 WuB.TengH.ZhangL.LiH.LiJ.WangL.et al (2015)
The addition of glucagon is what makes retatrutide different from most current weight loss injections
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Instead of just raising blood sugar, it: Increases energy expenditure (your body burns more calories at rest) Enhances fat oxidation (your body preferentially burns fat for fuel) Improves liver fat metabolism (reduces fatty liver disease) Boosts metabolic rate without causing dangerous blood sugar spikes The GLP-1 and GIP components keep blood sugar in check while the glucagon component supercharges fat burning
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