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Landes Bioscience

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Its effects on appetite, glucose regulation, and metabolic balance make it a valuable peptide for long-term metabolic studies

A free interaction checker is available from Drugs.com (see Drugs.com interactions checker)

PT-141s cyclic heptapeptide structure incorporating a D-Phe residue at position 4 and a cyclised structure via an Asp-Lys lactam bridge confers greater receptor binding stability and metabolic resistance than linear melanocortin peptides, while its chemical modification relative to -MSH shifts selectivity away from MC1R (peripheral pigmentation) toward central MC3R and MC4R, the receptors most relevant to sexual behaviour circuitry

Adv Exp Med Biol (1994) 370:4116