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Low B12 levels can show up in many ways

Under the International Nomenclature of Cosmetic Ingredients it is copper tripeptide-1, and it appears in serums, creams, and scalp products marketed for skin and hair appearance

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While the daily dose was sufficient to maintain serum B12 levels above 156 pmol/l in almost all subjects, the weekly dose was only able to do so in 74% of subjects (Sanz-Cuesta, 2020)