According to clinical observations reported by Integrative Medicine of Los Angeles, an intramuscular B12 injection is absorbed more slowly over a longer time frame compared to an IV infusion, which delivers the nutrient immediately into the vasculature
It blocks an enzyme called NNMT, which consumes nicotinamide, a building block cells use to make NAD+
However, the progress is slow
AOD-9604 Before and After: Realistic Timeline by Week Based on the available clinical data, the mechanism of action, and the pharmacokinetics of subcutaneous administration, here is a realistic timeline of what AOD-9604 users may experience
Molecular weight: ~1815.1 g/mol
While AOD-9604 works systemically once absorbed, injecting near the target fat depot provides the highest local concentration during the brief peak activity window