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While SP-analog has been shown to reduce weight gain, and hence likely aid in treatment of diabetes and obesity (Asakawa et al., 2003), when considering the dimer alone this attenuation may not be beneficial

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Neuroinflammation is primarily mediated by activated microglia and astrocytes that release pro-inflammatory cytokines, thereby exacerbating central nervous system (CNS) inflammation (Ahmad et al

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279 Suppressing p53 activity significantly improves senescence-like changes and insulin resistance in mice with T2D-like disease