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many studies show only modest or no significant benefit
What's in the other ~2.7%
doi: 10.1186/s12916-022-02537-4 10 TuttleKRAgarwalRAlpersCEBakrisGLBrosiusFCKolkhofPet al
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This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience
These experiments suggest a half-life longer than two days
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