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Zinc Zinc is a trace mineral involved in over 300 body processes, influencing everything from gene activity and immune signaling to wound healing and brain health
326,327 Importantly, zinc may inhibit neuronal NMDA glutamate receptors, which are dysregulated in those with depression, and raise BDNF levels, which can promote neuroplasticity
But long-term compliance may be affected by dietary habits, chewing function, or socioeconomic factors in the elderly
36,38,39 Compared to oral administration, whereby under 10% actually enters the blood stream, 52 orobuccal administration leads to over 80% absorption directly into the systemic circulation
Pediatr Nephrol 12:365370
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