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Presented for research literature review only Meister A (1984)
Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells
Specificity is the primary obstacle: most DHHC enzymes have multiple substrates, and broadly inhibiting their activity may lead to unforeseen off-target effects
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The impact of IGF-1 LR3 on human-derived tissue models and preclinical studies reveals significant anabolic and regenerative effects, especially in muscle and connective tissue systems
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