If you have certain digestive disorders, including pernicious anemia, or have had gastric bypass surgery, oral B12 will simply not work because you can't absorb it correctly
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
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Rare but potentially serious adverse effects require careful consideration and monitoring
Adults over 50 Your ability to absorb B12 decreases with age
As an investigational peptide, any legitimate clinical use involves a licensed provider, a prescription, and compounding through a licensed pharmacy