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GLP-1 receptors are expressed not only in the gut and pancreas but also in brain regions involved in reward, motivation, and stress regulation, including areas linked to the mesolimbic dopamine system the core circuitry of addiction
While most are mild , practitioners should be aware of both common and rare reactions: Common : mild soreness at the injection site, flushing, or temporary nausea
Whilst not reaching the maintenance dose of Wegovy could be considered as an off license use of the medication, under the appropriate qualified supervision a medical judgement can be made on the appropriateness of continuation of treatment on a lower dose
Probably 10% of American women
Christopher M Stevens for lab assistance
As demand increases for GLP-1 medications, replicating the rigorous weight monitoring protocols used in clinical trials can be challenging
