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10.1074/jbc.C400325200 J
Protein purification Prior to each protein analysis the target protein has to be separated from a complex mixture to focus on the function without influences from other molecules, making protein purification to one of the main applications in biotechnology
Vitamin B12 (cobalamin) is an essential water-soluble vitamin that plays a crucial role in red blood cell formation, neurological function, and DNA synthesis
Hence, a peptide was designed by substituting the negatively charged residues D42, D48, D49, E51, E56, and D57 within the p53 TAD PEP with alanine to increase its binding affinity to FOXO4 FHD and enhance membrane penetration
In another study, published in Clinical Pharmacokinetics , researchers also found that water intake, fasting time and meal timing can affect the amount of the drug that enters the bloodstream
Schizophr Res 84 : 214221
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