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Toxicology assessments in rats found no organ toxicity at doses up to 10 mg/kg (approximately 1000x the effective dose), no mutagenicity in Ames testing, and no teratogenic effects

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All products referenced are for laboratory research, analytical, and invitro use only

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This is why its effects on sexual function appear even in the absence of direct physical stimulation

Kwok AMF, Morosin T (2019) Leflunomide-induced colitis in association with enterocutaneous fistula in an immunosuppressed patient with renal transplant and rheumatoid arthritis