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What actually exists is (a) laboratory permeability data suggesting the molecule can cross membranes, and (b) animal efficacy studies that used injection , not oral gavage

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Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht von Graefes Archiv fr Klinische und Experimentelle Ophthalmologie

Stennis Watson, et al

However, when amounts of fat exceed the adipose tissues storage capacity and overwhelm adipose tissues functional capacity, fat begins to deposit ectopically in other metabolically relevant organs, such as the liver, skeletal muscle, kidney, and pancreas