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PubMed Dalmasso G, et al

520 This finding emphasizes the importance of considering metabolic status in cancer treatment and the necessity for further research in this area

University of WisconsinWilliam W

In 2025 , Novo Nordisk announced positive Phase 3 ESSENCE trial results evaluating semaglutide for early Alzheimers disease, demonstrating potential neuroprotective effects and opening new therapeutic opportunities

Additionally, GLP-1 suppresses glucagon secretion from pancreatic alpha cells, slows gastric emptying to moderate the rate at which nutrients enter the bloodstream, and acts on the brain to promote satiety and reduce appetite

For example, sitagliptin and vildagliptin treatment could lower systolic blood pressure (SBP) independently of a reduction in blood glucose (Table 1)