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If you take insulin or other diabetes medications, your doses may need adjustment downward as semaglutide lowers blood glucose
[9] [10] This dual action helps regulate blood glucose levels without causing hypoglycaemia when glucose concentrations are normal, though the risk of hypoglycaemia increases when used with insulin or sulfonylureas
Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, and glucagon) that remains unlicensed in the UK
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However, a number of case reports and analysis of adverse effect databases raised the possibility that the drugs increase the incidence of acute pancreatitis
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