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Additional information Peer review information Nature Metabolism thanks Dominique Langin and the other, anonymous reviewers for their contribution to the peer review of this work

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Dosage Precautions Treatment with this drug should be administered with caution if the animal has chronic renal failure

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All the vitamins in this injection are naturally present in foods and are essential to the human body

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Storage Requirements: Unopened lyophilized AOD-9604 should be stored in a refrigerator at 2-8C (36-46F) and protected from light

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Common side effects Injection-site reactions: mild redness, tenderness, swelling, occasional bruising - usually resolve within hours Skin flushing / warmth - brief, related to vasodilation Transient fatigue in the first 12 weeks of intensive protocols Mild headache - usually dose-related Higher-dose theoretical concerns Copper accumulation - each 2 mg injection adds roughly 0.03 mg of elemental copper, trivial next to the 0.92.2 mg from a normal diet

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End Users do not act for or on behalf of the CMS

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