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Curr Opin Pharmacol 7, 398403 (2007)

Pharmacologic Treatment of Overweight and Obesity in Adults

Sam Hawley: Oh, wow

The additional glucagon receptor activation increases energy expenditure and fat burning, producing approximately 6 percentage points more weight loss in clinical trials (28.7% vs 22.5%)

While its primary action involves p53 release, the modulation of FOXO4-related pathways intersects with cellular stress-response systems