glp 1 sticker peaka patches Abbey Sharp • Registered Dietitian Glutamine supports muscle recovery and tone How to Wear GLP-1 Patches:

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Cagrilintide vs semaglutide (Wegovy/Ozempic) Mechanism: Cagrilintide: Amylin receptor agonist Semaglutide: GLP-1 receptor agonist Different pathways Weight loss: Cagrilintide alone: 10-12% Semaglutide alone: 10-15% Similar efficacy monotherapy Gastric emptying: Cagrilintide: Very strong delay Semaglutide: Moderate delay Cagrilintide more powerful Side effects: Cagrilintide: More GI effects (stronger gastric slowing) Semaglutide: Moderate GI effects Cagrilintide harder to tolerate for some Availability: Cagrilintide: Investigational (not approved) Semaglutide: FDA approved, widely available Semaglutide easier to obtain currently Combination potential: Synergistic together (CagriSema) 15-25% weight loss combined Best of both mechanisms Verdict: Similar monotherapy efficacy, but combine for maximum results

Further studies assessing the temporal relation between glucose control, weight loss, and dermatologic improvement following initiation of GLP-1RAs are needed to determine the efficacy of GLP-1RAs and the mechanism by which they act

10.1164/rccm.201003-0442OC

If cholelithiasis is suspected, gallbladder studies and appropriate clinical follow-up are indicated Hypoglycemia: Adult patients with type 2 diabetes on an insulin secretagogue (eg, a sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia with use of Saxenda

Medical nutrition therapy interventions provided by dietitians for adult overweight and obesity management: an academy of nutrition and dietetics Evidence-Based practice guideline