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(10 pts) Oxidant Reductant RE(V) Succinate -CO a-ketoglutarate 2 -0.67 Acetate Acetaldehyde 2 0.60 Ferredokan (oxidized) Ferredoxin (reduced) 1 -043 2 H HE 2 042 NAD: NADH-H 2 -0.32 NADP NADPH-H 2 -0.32 Lipoate oxidured) Lipoate reduced 2 -0.29 Glutathione (oxidized) Glutathione (reduced) 2 03 EAD EADH 2022 Acetaldehyde Ethanol 2030 Pyruvate Lactate 2 019 Fumarate Succinate 003 Cytochrome (+3) Cytochrome (+2) 0.07 Dehydroascorbate Ascorbate 2 0.08 Ubiquinone (oxidured) Ubiquinone (reduced) 2 010 Cytochronne(+3) Cytochrome (2) 0.22 Fe(+3) Fe (-2) 0.77 02-27 HO 2 2 1

doi: 10.1111/bcp.14091 124 SeinoYFukushimaMYabeDSeinoYFukushimaMYabeD

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- Microneedling Effect: Infused with spicules, our treatment delivers active ingredients effectively, providing a tingling and micro-stimulation for enhanced results

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SG and AV collaborated to text and figures