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#Diabetes #insulin #drugdiscovery #innovation #medicine #clinicaltrials #genetic #drugdevelopment #drugdelivery To view or add a comment, sign in A class of diabetes drugs called GLP-1 receptor agonists works by directly stimulating the pancreas to release more insulin, which lowers blood sugar
Adipose tissue
Semaglutide (Wegovy/Ozempic) is the closest FDA-approved alternative, targeting the GLP-1 receptor that tirzepatide also activates
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In SURMOUNT-1, 72 weeks of tirzepatide induced mean WL of 1622.5% in people without diabetes compared to 2.4% with placebo, with no sign of the weight plateauing, suggesting that there may be further WL with long-term use [46]
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