Common (may affect up to 1 in 10 people) low blood sugar (hypoglycaemia) when this medicine is used with oral diabetes medicine other than sulfonylurea or insulin being sick (vomiting) upset stomach or indigestion inflamed stomach (gastritis) the signs include stomach ache, feeling sick (nausea) or being sick (vomiting) reflux or heartburn also called gastro-esophageal reflux disease stomach pain bloating of the stomach constipation tiredness less appetite gas (flatulence) 5 increase of pancreatic enzymes (such as lipase and amylase) shown in blood tests
20 Systematic reviews: Oral vitamin B 12 replacement for the treatment of pernicious anemia 21 Relevant articles were identified by PubMed search from January 1, 1980 to March 31, 2016, focusing on patients with pernicious anemia
Oral supplements often dont provide the full benefits due to limited absorption in the digestive tract
Wegovy (2.4mg weekly) is FDA-approved for chronic weight management
Insurers also introduced novel metabolic health programs: for instance, in 2026 CVS Caremark announced a Weight Management UM Bundle to automatically apply evidence-based PA criteria on new GLP-1 agents, reducing ad-hoc appeals ( [34] ) ( [35] )
For many people, this makes long-term treatment impossible regardless of how effective the medication is