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The phase Ib TROPION-Lung02 trial is a dose-escalation and -expansion study evaluating Dato-DXd (4 or 6 mg/kg) combined with pembrolizumab (doublet) with or without platinum agents (triplet therapy) in both previously untreated and pre-treated patients with metastatic NSCLC without actionable genomic alterations

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However, B12 supplementation will only help if youre actually deficient