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This usually settles within a couple of weeks as the body adjusts

The molecule is the same whether it reaches a patient as an FDA-approved brand product or as a compounded preparation

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In addition, in vitro studies have shown that recombinant TTR amyloid aggregates are internalized by human cardiac fibroblasts, which subsequently secrete IL-6 and IL-8, providing mechanistic evidence that TTR aggregates can trigger inflammatory responses in cardiac cells [77]

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