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This transporter has similarities to the cystic fibrosis transmembrane conductance regulator (CFTR), which has been shown to be responsible for GSH flux from lung airway epithelial cells (Kogan et al , 2003), suggesting that ABC transporters might function in the transport of glutathione in mammalian cells

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View Study Ohara H, Matsumoto H, Ito K, et al

doi:10.2214/ajr.165.6.7484597 4

The increase in cAMP levels triggers a series of events, including the activation of protein kinase A (PKA)

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