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A clinical study (10) has suggested that the peptide may lead to an immediate increase in sleep pressure and resulted in a 59% increase in sleep within two hours of initiating DSIP experimentation

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doi:10.1039/C0SM01218A

doi:10.1080/10408398.2021.1875977

This indicates that DPP-4i treatment is in some cases attempted before switch to GLP-1 RAs, as the cost of DPP-4is is lower, and GLP-1 RAs (during the period in which this study was conducted) required injections