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Central abdominal obesity also leads to reduced lung volume, which decreases caudal tracheal traction and further increases risk of airway collapse [54]

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PRISMA 2020 Checklist Figure & Data References Citations Citations to this article as recorded by The efficacy and safety of dual GIP/GLP1 receptor agonists (tirzepatide) in diabetes and obesity: a systematic review and network meta-analysis Karolina Hoffmann, Micha Michalak, Manfredi Rizzo, Viviana Maggio, Anna Paczkowska Expert Opinion on Drug Safety.2026