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Taken together, ferroptosis is a PCD mechanism intricately associated with iron metabolism, lipid peroxidation, and antioxidant systems (Figure 4A)
Safety profile : Are there potential adverse effects or interactions
GCL is a heterodimer comprising a catalytic subunit (GCLC) and a regulatory subunit (GCLM) 47
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We observed no evidence of dominance effects ( P = 0.80), indicating that the allelic dosage of the T allele contributes to efficacy in an additive manner
Key References Flint A, Raben A, Astrup A, Holst JJ
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