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There are significant side effects that we need to be aware of pancreatitis, blindness, increased risk of thyroid cancer, gallbladder attacks, that all need to be monitored. Kainkaryam said the medications require patients to be engaged in a full program with clinicians who know how they work

For patients not planning pregnancy, contraception may be discussed since the medication must be discontinued before conception

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However, this theoretical mechanism has not been clinically established