Of course, bulk MTG cards will cost more when you purchase singles so that your LGS can make some money in the process
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(Choose any number of permanents and/or players, then give each another counter of each kind already there.) If the last time counter is removed from a permanent with vanishing and the sacrifice ability is countered, that permanent will remain on the battlefield indefinitely with no time counters on it
To be honest...I don't really know
You can easily see that the difference is huge
Still though, a sealed booster box of this set will set you back a cool $3,000 and with good reason thanks to notable chase cards such as the eminently powerful ramping tool Grim Monolith, the Squirrel kindred powerhouse Deranged Hermit and artifact recursion machine Goblin Welder